Bellyache Bush

Several human and veterinary uses in traditional medicine are described for different parts (leaves, stems, roots, seeds, and latex) and preparations (infusion, decoction, and maceration, among others) based on this plant, by different routes (oral or topical). The most frequent reports concern its antihypertensive, anti-inflammatory, antiophidian, analgesic, antipyretic, antimicrobial, healing, antianemic, antidiabetic, and antihemorrhagic activities, among many other examples. Other uses are also related to this plant, such as biodiesel production, pesticide, insecticide, vermifuge, ornamentation, and even its use in religious rituals. The American Instructor, a reference book written by Benjamin Franklin, states it can be used as an abortion tonic, along with pennyroyal:

Now I am upon Female Infirmities, it will not be unreasonable to touch upon a common Complaint among unmarried women, namely The Suppression of the Courses. This don't only disparage their Complexions, but fills them besides with sundry Disorders. For this Misfortune, you must purge with Highland Flagg (commonly called Belly ach Root) a Week before you expect to be out of Order; and repeat the same two Days after: the next Morning drink a Quarter of a Pint of Pennyroyal Water, or Decoction, and as much again at Night when you go to Bed. …