False abura
Mitragyna inermis
Also calledAglal (Hassaniya, Mauritania) · Koyli (Pulaar) · Hos (Wolof) · Khilé (Soninke) · Yeblig (Talensi, Ghana)
A small, bushy West African tree that grows near water, used by healers from Mauritania to Ghana for liver complaints, malaria, epilepsy, diabetes and childbirth. All evidence so far comes from lab and animal studies; no human trials or human safety data were found.
What it is used for
- MalariaLimited
Used for malaria in Mauritania. Methanol and ethanol–water extracts of stem bark and twigs were highly active against drug-sensitive and multidrug-resistant Plasmodium falciparum in the lab; ellagic acid was the active compound isolated (IC50 0.84–1.62 µg/ml). No animal or human efficacy data were found.2,3
- Epilepsy and seizuresLimited
Leaf and seed decoctions are used for epilepsy in Mauritania. Stem-bark and leaf extracts delayed tonic seizures induced by pentylenetetrazol in mice; oxindole alkaloids (pteropodine, isopteropodine, mitraphylline, corynoxeine) were isolated.3,5
- Blood sugar and diabetesLimited
Herbalists in Burkina Faso use it for diabetes and hypertension. Leaf, stem and root fractions inhibited formation of advanced glycation end-products in a test-tube model; earlier in vivo antidiabetic effects are reported in the literature but no human trials were found.6
- Intestinal wormsLimited
Leaves are widely used in West African veterinary medicine against stomach worms of sheep and goats; the authors of a lab study measured anthelmintic activity of leaf extracts. No human data.8
- Liver healthTraditional
One of the plants most often included in multi-plant recipes by traditional healers in Burkina Faso for liver disease, chiefly the leaves and roots.4
- Childbirth and labourTraditional
Talensi healers in northern Ghana boil the root, stem or leaves to aid delivery and give strength to pregnant women; in Mauritania leaf decoctions are used for complications after childbirth.3,7
How it is prepared
decoction
Leaves, roots or stems boiled in water and drunk; in Burkina Faso usually combined with other plants. No attributed doses were found.
Liver health · Childbirth and labour
Amounts are as recorded by the named source, not a recommendation.
Safety
- Pregnancy
- Insufficient data
- Breastfeeding
- Insufficient data
Toxicity
No human safety studies were found. Extract fractions showed no toxicity to mouse fibroblast cells up to 500 µg/ml in the lab. Its traditional use around childbirth has not been studied for safety.
In the healing traditions
- African traditional medicine
Aglal / Koyli / Hos (Mauritania)
Leaves for complications of the puerperium, constipation and rheumatism; leaves and seeds for malaria and epilepsy; leaf decoction for syphilis.
- African traditional medicine
Yeblig (Talensi, Ghana)
Root, stem and leaves boiled and drunk for swollen legs, waist pain, to improve appetite and aid delivery, and as an additive in fracture treatment; ground root as a paste applied to the skin.
- African traditional medicine
Mitragyna inermis (Burkina Faso)
Leaves and roots in healers' multi-plant recipes for liver disease; used by herbalists for diabetes and hypertension.
Active compounds
- pteropodine, isopteropodine, mitraphylline, corynoxeine
- oxindole alkaloids isolated from the plant; proposed contributors to anticonvulsant activity in mice
- ellagic acid
- the compound most active against P. falciparum in the lab
- quinovic acid glycosides, sweroside
- isolated from roots; did not themselves inhibit glycation
History
Ethnobotanical surveys from Senegal to Cameroon record M. inermis, which often grows in pure stands near water. A 2020 countrywide survey of traditional healers in Burkina Faso listed it among the plants most often used in liver-disease recipes.
Sources
- 1.GBIF Backbone Taxonomy: Mitragyna inermis (Willd.) Kuntze
- 2.Hassan S et al. A bio-guided investigation of Mitragyna inermis unveils natural product isolates with potent cross-activity against sensitive and multidrug resistant Plasmodium falciparum strains in vitro. J Ethnopharmacol 2025 (abstract)
- 3.Yebouk C et al. Review and cross-cultural analysis of medicinal plants traditionally used in Mauritania. J Ethnobiol Ethnomed 2025
- 4.Tibiri A et al. Countrywide survey of plants used for liver disease management by traditional healers in Burkina Faso. Front Pharmacol 2020
- 5.Ouédraogo RJ et al. Antiseizure activity of Mitragyna inermis in the pentylenetetrazol-induced seizure model in mice. Turk J Pharm Sci 2024
- 6.Ouédraogo RJ et al. Inhibition of advanced glycation end-products by Tamarindus indica and Mitragyna inermis extracts and effects on human hepatocyte and fibroblast viability. Molecules 2023
- 7.Azanlerigo E et al. Ethnobotanical study of indigenous knowledge on medicinal plants used in the Talensi District of the Upper East Region of Ghana. Open Res Afr 2025
- 8.Toklo PM et al. UPLC-QToF-ESI-MS identification and anthelmintic activity of Mitragyna inermis. Heliyon 2023 (abstract)
Reference, not prescription. Nothing here is medical advice. Herbs can interact with medicines and be dangerous in pregnancy; tell your doctor or pharmacist about anything you take.