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Tatarian aster

Aster tataricus

También llamadaZi wan 紫菀 (Chinese) · Fan huncao (Chinese) · Shion シオン (Japanese) · Gaemichwi 개미취 (Korean)

A tall purple-flowered aster of north-east Asia whose dried root and rhizome, zi wan, has been a Chinese cough and phlegm medicine since the Shennong Bencao Jing. Modern support comes from animal and cell studies only, and animal studies point to liver toxicity at high doses or with long use.

Para qué se usa

  • Ethanol extracts relaxed guinea-pig airway smooth muscle and showed anti-asthmatic activity in animal models. It appeared in 205 of 218 Chinese prescriptions analysed for cough-variant asthma, but it has not been tested on its own in people.1,2

  • Bronquitis
    Limitada

    In animal studies Zi Wan San (root with other herbs) and root extracts reduced airway inflammation; human evidence is limited to multi-herb Chinese formulas.2

  • A root extract inhibited influenza A, Newcastle disease and herpes simplex viruses in cell culture and improved survival of mice given lethal influenza when given beforehand. Laboratory and animal work only.4

  • Tos
    Tradicional

    The Chinese Pharmacopoeia (2020) lists it for cough with excessive phlegm, wheezing, chronic cough and coughing up blood. In mice, shionone and epi-friedelanol from the root reduced ammonia-induced coughing and extracts increased phlegm clearance; honey-processed root was more effective than raw. No clinical trials of the herb alone were found.1,2

  • Estreñimiento
    Tradicional

    Older Chinese medical records describe it as relieving constipation and difficult urination; untested.1,2

Cómo se prepara

decoction

The dried root and rhizome, raw or honey-fried, boiled in water, usually with other herbs in a formula.

Chinese Pharmacopoeia (2020), as cited in a 2025 review: 5–10 g.

Tos

food

In China, Korea and Japan young spring leaves are blanched and eaten as a vegetable; China permits the plant as both food and medicine within a limited scope and dose.

Las cantidades son las que registra la fuente citada, no una recomendación.

Seguridad

Embarazo
Datos insuficientes
Lactancia
Datos insuficientes

Toxicidad

Reviews describe it as generally considered clinically safe at pharmacopoeial doses, but animal studies point to the liver: the oral LD50 of a 75% ethanol extract in mice was 15.74 g/kg; subchronic dosing in rats (0.34 g/kg/day) caused liver damage concentrated in the petroleum-ether and ethyl-acetate fractions; and one fraction caused acute liver injury and death in mice at 0.052 g/kg. Saponins are haemolytic, so crude extracts are not suitable for intravenous use. Human toxicity data are lacking; risk appears greater at high doses or with long use.

En las tradiciones curativas

  • Traditional Chinese Medicine

    Zi wan (紫菀)

    Acrid, bitter and warm, belonging to the Lung channel; used to clear lung qi, calm adverse-rising qi, relieve cough and resolve sputum. The Shennong Bencao Jing says it relieves cough, regulates cold and heat in the chest and calms the five viscera; later materia medica add coughing of blood, pulmonary abscess and children's convulsions. Honey-frying is said to make it better at moistening the lungs and relieving cough.

    Shennong Bencao Jing; Xin Xiu Ben Cao; Chinese Pharmacopoeia 2020

Compuestos activos

shionone
triterpene used by the Chinese Pharmacopoeia as the quality marker; antitussive and anti-inflammatory in animal studies
astins A–P
chlorinated cyclic pentapeptides from the root; structurally similar to the hepatotoxic fungal toxin cyclochlorotine; at least astins C, F and G are made by the endophytic fungus Cyanodermella asteris living in the plant
triterpenoid saponins
considered expectorant; haemolytic, so crude extracts are unsuitable for injection
quercetin, kaempferol, ferulic acid
identified as antiviral constituents of the aqueous fraction in one study

Historia

Zi wan is recorded in the Shennong Bencao Jing and has been used in Chinese medicine for more than 2,000 years, traditionally processed with honey, vinegar, wine or ginger and today mainly honey- or bran-fried. In 2026 researchers showed that at least some of its signature astin peptides are made not by the plant but by a fungus living inside it.

Fuentes

  1. 1.Fan XL et al. An updated and comprehensive review of the morphology, ethnomedicinal uses, phytochemistry, and pharmacological activity of Aster tataricus L. f. Heliyon 2024
  2. 2.Zhang X et al. Aster tataricus L. f.: a review on the botany, phytochemistry, ethnopharmacology, pharmacology, toxicology and comprehensive utilization. Front Pharmacol 2025
  3. 3.Barrera-Adame DA et al. Spatial distribution of astins in Aster tataricus and their production by Cyanodermella asteris. J Nat Prod 2026
  4. 4.Gamage N et al. Aster tataricus extract and its active compounds display a broad spectrum of antiviral activity in vitro and in vivo. Chin Med 2025 (abstract)
  5. 5.EMA/HMPC/228356/2012 Rev. 2: European Union herbal monographs — overview of recommendations for the paediatric population (2023)
  6. 6.GBIF Backbone Taxonomy: Aster tataricus L.fil.

Referencia, no receta. Nada de esto es consejo médico. Las hierbas pueden interactuar con medicamentos y ser peligrosas en el embarazo; informa a tu médico o farmacéutico de todo lo que tomes.